ISDIN Isdinceutics Retinal Advanced Night Serum – Retinaldehyde + Melatonin, 50 ml

ISDIN Isdinceutics Retinal Advanced Night Serum

Designed as a smart, dual-phase night treatment, this serum blends retinaldehyde with melatonin and bakuchiol, finished with a Soothing Complex that activates at the moment of application. Used nightly, it aims to soften texture and refine the look of fine lines, with clinical data noting notable wrinkle-related changes after four weeks. The formula is built to be gentle enough for a broad range of skin types, including sensitive skin, thanks to its stability and careful ingredient balance that stays separate until you apply.

On your skin, the experience is meant to feel silky and light: a fast-absorbing finish that leaves a comforting, non-greasy feel as you transition into your nighttime routine. The two-phase design helps keep actives stable until use, so you can trust the moment you apply, the ingredients are ready to work. With retinaldehyde as a potent component, paired with melatonin and bakuchiol, the serum supports a sense of renewal without heaviness. In clinical observations, users reported up to a 43% reduction in wrinkles after four weeks, illustrating the potential for visible changes when used consistently alongside a complete skincare regimen.

Key benefits

• Dual-phase design preserves stability and potency until application.
• Retinaldehyde provides strong youth-boosting properties when used nightly.
• Melatonin and bakuchiol contribute to a calming, nighttime ritual.
• Soothing Complex supports comfort during application, with broad skin-type compatibility.
• Clinical data indicate potential wrinkle improvement after four weeks.

What to expect and how to use

• Silky, fast-absorbing texture with a lightweight finish.
• Suitable for all skin types, including sensitive skin.
• Best used as part of a nightly routine on cleansed skin.
• Pair with moisturizer if you want extra hydration.

How to incorporate into your night routine

After cleansing, apply a small amount to face and neck, then follow with moisturizer if desired. If you are new to active ingredients, begin with a smaller amount and gradually adjust frequency to your comfort level. Consider a patch test before full use and monitor for any tingling or irritation, adjusting usage as needed.